NCT07044726

Betadine vs Sterile Water for Periurethral Preparation

Betadine vs Sterile Water for Periurethral Preparation Prior to Straight Catherization in the Clinic Setting: A Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 148 (estimated)
• Sponsor: University of Louisville · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water (water that has been treated to remove bacteria and living organisms) vs Betadine also known as Povidone-Iodine (a medical grade cleaning solution) changes the rates of bacteria in the urine after a temporary catheter, or draining tube, is placed into the bladder. Chemical antiseptics, including Betadine, are the current standard of care. An additional goal of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water vs betadine changes the amount of discomfort or pain patients experience with placement of a temporary catheter, or draining tube, in the bladder.

Conditions

• Catherization
• Urinary Tract Infection Bacterial

Interventions

Type	Name	Description
DRUG	Povidone-Iodine	Providone-Iodine for periurethral preparation
DRUG	Sterile water	Sterile water for periurethral preparation

Timeline

• Start date: 2025-06-23
• Primary completion: 2028-05-21
• Completion: 2028-05-21
• First posted: 2025-07-01
• Last updated: 2025-07-01

Locations

2 sites across 1 country: United States

Regulatory

• FDA-regulated drug study