NCT07044635

Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.

Radiation Therapy in Reduced Dose and Hypofractionated Schedule After Trans-Oral Robotic Surgery in Intermediate Risk HPV-Mediated Oropharyngeal Squamous Cell Carcinoma

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 42 (estimated)
• Sponsor: University of Utah · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to evaluate if a shorter course of therapy can improve the quality of life in patients receiving radiation therapy after trans-oral robotic surgery.

Conditions

• Oropharyngeal Squamous Cell Carcinoma
• HPV-mediated Oropharyngeal Squamous Cell Carcinoma

Interventions

Type	Name	Description
RADIATION	Radiation Therapy	Reduced dose and Hypofractionated radiation therapy

Timeline

• Start date: 2025-07-23
• Primary completion: 2029-08-01
• Completion: 2030-08-01
• First posted: 2025-07-01
• Last updated: 2026-02-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study