NCT07043413

Thrombus Analysis of Ischemic Stroke

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Patients with acute ischemic stroke who have undergone endovascular thrombectomy will be eligible to be included, and thrombus will be collected after obtaining informed consent. Enrolled patients will receive a comprehensive diagnostic evaluation and the best medical treatment according to recent stroke management guidelines. The mechanism of the stroke will be classified into atherosclerotic, cardiac embolism, others and unknown causes based on diagnostic workup. Patients will be monitored in an outpatient clinic for vascular events including stroke recurrence, death, and bleeding events, which will continue for up to two years after the initial stroke event. Thrombus information related to RNA expression patterns and histological characteristics will be analyzed to classify the stroke mechanism and predict future vascular events after the initial stroke.

Conditions

• Cerebral Infarction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	thrombus analysis	Detailed expression pattern of RNA and histological characteristics will be investigated.

Timeline

• Start date: 2022-01-25
• Primary completion: 2028-12-31
• Completion: 2029-12-31
• First posted: 2025-06-29
• Last updated: 2025-06-29

Locations

1 site across 1 country: South Korea