Trials / Completed
CompletedNCT07042204
Effectiveness of E-prf Alone and in Combination With Bioactive Glass Nanoparticles in Grade II Furcation Defects
Effectiveness of Extended Platelet-Rich Fibrin (ePRF) Alone and in Combination With Bioactive Glass Nanoparticles in the Treatment of Grade II Furcation Defects
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Merna Nasser Mohamed Mostafa Ibrahim Elnahas · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to evaluate and compare the effectiveness of extended platelet-rich fibrin (ePRF) alone and in combination with bioactive glass nanoparticles in the treatment of grade II furcation defects clinically and radiographically.
Detailed description
A total of 30 grade II furcation defects will be randomly divided into three groups as follows: Group I: 10 grade II furcation defects will be treated by extended platelet-rich fibrin (ePRF) alone. Group II: 10 grade II furcation defects will be treated by bioactive glass nanoparticles mixed with extended platelet-rich fibrin (BGn+ePRF). Group III: 10 grade II furcation defects will be treated by bioactive glass nanoparticles with collagen membrane.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Group I (extended platelet-rich fibrin) | mucoperiosteal flap will be raised through sulcular incisions Debridement of granulation tissue from the osseous defect and furcation will be filled with (ePRF) at the first group |
| PROCEDURE | Group II (bioactive glass nanoparticles mixed with extended platelet-rich fibrin) | bioactive glass nanoparticles mixed with extended platelet-rich fibrin (BGn+ePRF) |
| PROCEDURE | Group III (bioactive glass nanoparticles and covered by a collagen membrane) | bioactive glass nanoparticles and covered by a collagen membrane |
Timeline
- Start date
- 2024-01-03
- Primary completion
- 2025-06-03
- Completion
- 2025-08-03
- First posted
- 2025-06-27
- Last updated
- 2026-01-13
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT07042204. Inclusion in this directory is not an endorsement.