NCT07041359

Pre-trial of Clinical Trial of Traditional Chinese Medicine Treatment for Elderly Patients With Coronary Heart Disease Who Are Still Symptomatic After Optimal Medical Treatment

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: China National Center for Cardiovascular Diseases · Other Government
• Sex: All
• Age: 75 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

To explore the effectiveness of compound Danshen Dripping Pill and Qishen Yiqi Dripping Pill in the elderly population with coronary heart disease and the safety of multiple medications

Detailed description

This study is a prospective, double-blind, randomized controlled clinical trial, which aims to explore the effectiveness and safety of polypharmacy in the elderly population of stable angina patients, and make up for the limitations of clinical treatment. As commonly used traditional Chinese medicine preparations, the efficacy and safety of compound Danshen Dripping Pill and Qishen Yiqi Dripping Pill have been supported by previous studies, providing a solid theoretical basis. The study design adopts scientific and reliable clinical trial methods, and the treatment plan combines Western medicine treatment and traditional Chinese medicine intervention, which has high clinical application value. In the actual clinical treatment, due to the complex medical history of elderly patients, they often have multi-vessel coronary artery lesions, and the treatment tolerance is worse than that of young people, so although they are accompanied by angina pectoris, the treatment methods are relatively limited. This study provides evidence of the efficacy and safety of drugs for the treatment of elderly patients with angina pectoris through the combination of Chinese and Western treatments, which can help make up for the dilemma of limited clinical treatment methods.

Conditions

• Coronary Arterial Disease (CAD)

Interventions

Type	Name	Description
DRUG	Compound Danshen Dripping Pills	The experimental group used compound Danshen dripping pills as an intervention on the basis of conventional western medicine treatment.
DRUG	Qishen Yiqi Drop Pills	The experimental group used Qishen Yiqi dripping pills as an intervention on the basis of conventional western medicine treatment.
DRUG	Placebo	Intervention with placebo on the Basis of optimal medical treatment

Timeline

• Start date: 2025-08-18
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2025-06-27
• Last updated: 2025-09-29

Locations

1 site across 1 country: China