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Not Yet RecruitingNCT07040670

Diagnostic Yield and Safety of Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

Comparison of the Diagnostic Yield and Safety Between Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration and Endobronchial Ultrasound-Guided Transbronchial Mediastinal Cryobiopsy: a Randomised Controlled Trial

Status
Not Yet Recruiting
Phase
N/A
Study type
Interventional
Enrollment
469 (estimated)
Sponsor
China-Japan Friendship Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Comparison of the Diagnostic Yield and Safety Between Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration and Endobronchial Ultrasound-Guided Transbronchial Mediastinal Cryobiopsy in patients with mediastinal and/or hilar lymphadenopathy.

Conditions

Interventions

TypeNameDescription
PROCEDUREConfocal laser endomicroscopy-assisted endobronchial ultrasound-guided transbronchial needle aspirationFirst, use the EBUS needle to create a hole in the airway wall. Then, insert the CLE into the lymph node via this hole and detect the lymph node. When the specific pathological finding is detected by CLE, record the location. Finally, using the needle to perform EBUS-TBNA in the area under EBUS guidance.
PROCEDUREEndobronchial ultrsound-guided Mediastinal cryobiopsyUsing the cryoprobe to perform EBUS-TBMC three times per person.

Timeline

Start date
2025-07-01
Primary completion
2027-07-01
Completion
2027-07-01
First posted
2025-06-27
Last updated
2025-06-27

Source: ClinicalTrials.gov record NCT07040670. Inclusion in this directory is not an endorsement.