NCT07040423

MRI-Based Assessment of Local Anesthetic Spread in the PENG Block Compartment

Evaluation of Local Anesthetic Distribution in the PENG Block Compartment Using Pelvic MRI

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (estimated)
• Sponsor: Campus Bio-Medico University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study uses MRI imaging to evaluate the spread of local anesthetic following the administration of a pericapsular nerve group (PENG) block. The goal is to determine whether a distinct fascial plane exists between neurovascular structures, potentially explaining the block's observed clinical effectiveness.

Detailed description

The pericapsular nerve group (PENG) block has demonstrated promising clinical results in providing analgesia for hip-related pain, particularly in patients with femoral neck fractures or undergoing hip surgery. However, the exact mechanism of action and spread of local anesthetic remain poorly understood. This pilot study aims to use magnetic resonance imaging (MRI) to visualize the distribution pattern of the injectate after PENG block administration. High-resolution MRI scans will be obtained shortly after the procedure to assess the spatial relationship between the spread of local anesthetic, relevant anatomical structures (including the iliopsoas muscle, femoral artery, and femoral nerve), and potential fascial compartments. The findings will help to clarify the anatomic basis of the PENG block and may guide optimization of technique for enhanced clinical outcomes.

Conditions

• Total Hip Arthroplasty (THA)
• Postoperative Pain Management After Total Hip Arthroplasty

Interventions

Type	Name	Description
PROCEDURE	PENG Block	Preoperative ultrasound giuded PENG block (ropivacaine 0,5% 20mL)
PROCEDURE	Magnetic resonance imaging	The patient will undergo a pelvic MRI to assess anesthetic diffusion after PENG block

Timeline

• Start date: 2025-06-01
• Primary completion: 2026-05-01
• Completion: 2026-10-01
• First posted: 2025-06-27
• Last updated: 2025-06-27

Locations

1 site across 1 country: Italy