Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07039578

Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Light-Chain Amyloidosis

An Open-Label, Multi-Center, Phase II Clinical Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Relapsed or Refractory Primary Light-Chain Amyloidosis

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
90 (estimated)
Sponsor
Keymed Biosciences Co.Ltd · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

to Evaluate the Efficacy and Safety of CM336 (BCMA/CD3 Bispecific Antibody) in Adults with Relapsed or Refractory Primary Light-Chain Amyloidosis

Conditions

Interventions

TypeNameDescription
BIOLOGICALCM336 Injection(Low dose group)subcutaneous CM336 administration, step-up dosing, Dose and frequency of CM336 according to the protocol.
BIOLOGICALCM336 Injection(High dose group)subcutaneous CM336 administration, step-up dosing, Dose and frequency of CM336 according to the protocol.

Timeline

Start date
2025-07-25
Primary completion
2026-06-30
Completion
2029-07-31
First posted
2025-06-26
Last updated
2025-11-26

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT07039578. Inclusion in this directory is not an endorsement.