Trials / Completed
CompletedNCT07037706
Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 250 (actual)
- Sponsor
- Centre Hospitalier de Saint-Denis · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
This study looks at whether using macrolide antibiotics is helpful and safe in treating acute chest syndrome, a serious complication in people with sickle cell disease. It reviews past cases from three hospitals where patients were treated in intensive care. The goal is to understand if macrolides make a difference, what germs are involved, how useful lab tests are, and how well patients tolerate these antibiotics.
Conditions
- Sickle Cell Disease
- Acute Chest Syndrome
- Glucose-6-Phosphate Dehydrogenase Deficiency
- Anti-Bacterial Agents
- Macrolides
Timeline
- Start date
- 2023-06-01
- Primary completion
- 2024-06-01
- Completion
- 2024-06-01
- First posted
- 2025-06-25
- Last updated
- 2025-06-25
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT07037706. Inclusion in this directory is not an endorsement.