NCT07036445

Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain

Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain : a Prospective Study With Long Term Follow up

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Clinique du Sport, Bordeaux Mérignac · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and potentially safer option. A previous study showed that PRP was as effective as ESI in treating this condition, without major complications. This study aims to compare these two treatments over the long term (2 years).

Conditions

• Herniated Disc

Interventions

Type	Name	Description
PROCEDURE	Epidural Steroid Injection	Intervention consists of interlaminar CT guided epidural steroid injection
PROCEDURE	Epidural platelet-rich plasma injection	Intervention consists of interlaminar CT guided epidural platelet-rich plasma injection after recovery of plasma by blood sampling and centrifugation

Timeline

• Start date: 2025-09-11
• Primary completion: 2028-12-31
• Completion: 2028-12-31
• First posted: 2025-06-25
• Last updated: 2025-09-18

Locations

1 site across 1 country: France