NCT07034170

Skeletal Muscle Mass on Prognosis and Recovery in Clinical Trial

Comprehensive Interpretation of the Importance of Skeletal Muscle Mass on Prognosis and Recovery in Cardiac Arrest Survivors: From Machine Learning to Clinical Trial

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The objective of this research project is to develop an automated muscle mass measurement system based on computed tomography (CT) images using deep learning and artificial intelligence, and to construct a prognostic prediction model for patients who have experienced cardiac arrest and undergone resuscitation. The model will be validated using multicenter registry data and medical imaging. Furthermore, a clinical trial involving core muscle rehabilitation for post-resuscitation patients will be conducted to evaluate both short-term and long-term outcomes, aiming to comprehensively understand the impact of muscle mass on the prognosis of patients after cardiac arrest.

Conditions

• Out of Hospital Cardiac Arrest
• Inhospital Cardiac Arrest

Interventions

Type	Name	Description
BEHAVIORAL	Enhanced Rehabilitation Program	Participants in the intervention group receive an enhanced rehabilitation program, including muscular electrical stimulation, guided active rehabilitation sessions, and structured physical engagement during periods of consciousness. The intervention is designed to promote functional improvement in post-cardiac arrest patients.

Timeline

• Start date: 2025-06-01
• Primary completion: 2028-05-30
• Completion: 2028-12-31
• First posted: 2025-06-24
• Last updated: 2025-06-24

Locations

1 site across 1 country: Taiwan