NCT07033312

Therapeutic Effect of Oral Hyaluronic Acid on Knee Osteoarthritis

Therapeutic Effect of Combined Treatment of Oral Nutritional Supplement Based on Hyaluronic Acid With Hyaluronic Acid Intra-articular Injection on Symptomatic Knee Osteoarthritis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Taichung Veterans General Hospital · Academic / Other
• Sex: All
• Age: 60 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to investigate the effect of oral hyaluronate in patients with knee osteoarthritis. The main question it aims to answer is: the therapeutic effect in the combined treatment of oral nutritional supplement based on hyaluronic acid with hyaluronic acid intra-articular Injection on symptomatic knee osteoarthritis. Researchers will compare it to those who receive only hyaluronic acid injection to see if the combined treatment is better. Participants will receive a total of three months of oral hyaluronate or placebo agents.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	oral hyaluronate and injection	The patient receives oral hyaluronate and hyaluronate injection
DRUG	hyaluronate injection	The patient receives hyaluronate injection only

Timeline

• Start date: 2023-04-21
• Primary completion: 2025-08-01
• Completion: 2025-08-01
• First posted: 2025-06-24
• Last updated: 2025-06-24

Locations

1 site across 1 country: Taiwan