NCT07031466

Treatment Outcome in Patients After eCPR

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 74 (actual)
• Sponsor: University Hospital Ostrava · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study consists of two parts - retrospective and prospective. The aim of this study is to assess the quality of life in bio-psycho-social dimensions in patients after eCPR (extracorporeal cardiopulmonary resuscitation), in relation to their neurological outcome after the end of treatment and discharge from the Ostrava University Hospital (FNO). The study will focus on patients who underwent extracorporeal membrane oxygenation (ECMO) support after out-of-hospital cardiac arrest (OHCA) in the years 2022-2024.

Detailed description

Retrospective study Quantitative evaluation using data analysis from documentation. Patients on ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024 will be evaluated based on data from the documentation. Analysis of data from the documentation of selected patients will be performed, evaluating demographic data, comorbidities, duration of ECMO support, mortality, Cerebral Performance Category (CPC) score 30 days after CPR. Prospective study Quantitative assessment using validated questionnaire tools Patients connected to ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024, in whom a CPC score \>3 was detected after the 30th day from cardiac arrest and who were discharged from the FNO. As part of patient dispensary, these patients are electively invited to the PICS outpatient clinic in the FNO Ostrava. Individual interviews (filling out questionnaires) will be performed after obtaining informed consent in the Post-Intensive Care Syndrome (PICS) outpatient clinic at the University Hospital Ostrava, or telephone interviews conducted by the attending physician.

Conditions

• Cardiac Arrest (CA)

Interventions

Type	Name	Description
OTHER	Retrospective analysis of assigned treatment	Retrospective analysis of assigned treatment will be performed
OTHER	Quality of Life (SF-36)	The quality of life will be assessed using the SF-36 (Short-Form Health Subject Questionnaire).
OTHER	Quality of Life (EQ-5D)	The quality of life will be assessed using the EQ-5D (European Quality of Life Questionnaire)
OTHER	Hospital Anxiety and Depression (HADS)	Hospital Anxiety and Depression will be assessed using the HADS (Hospital Anxiety and Depression Scale)

Timeline

• Start date: 2022-01-01
• Primary completion: 2025-11-30
• Completion: 2025-11-30
• First posted: 2025-06-22
• Last updated: 2025-12-05

Locations

2 sites across 1 country: Czechia