Clinical Trials Directory

Trials / Completed

CompletedNCT07029191

Screening for Alterations in the Autonomic Nervous System

SYMPA-VEIN : Pilot Study Evaluating the ACCUVEIN Superficial Vein Visualization Device for the Detection of Alterations in the Autonomic Nervous System

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
12 (actual)
Sponsor
University Hospital, Angers · Other Government
Sex
All
Age
18 Years – 40 Years
Healthy volunteers
Accepted

Summary

Dysautonomia is an alteration of the autonomic nervous system that manifests itself in different forms, some of which are very disabling. Dysautonomia accompanies many pathologies. Its importance in public health is illustrated by an incidence of 20-70% in diabetes. It affects between 400,000 and 1.4 million patients in the French diabetic population alone. Dysautonomia is mainly investigated through alterations in the cardiovascular system's reactivity to various maneuvers. It involves a methodology that evaluates the functionality of the sympathetic nervous system. This methodology is reserved for specialized laboratories, limiting access to diagnosis. Dysautonomia is therefore commonly overlooked for lack of a simple, effective diagnostic tool. ACCUVEIN is an augmented-reality venipuncture device. It projects the network of superficial veins onto the patient's skin. Our aim is to show that ACCUVEIN is capable of objectivizing the venoconstriction caused by activation of the sympathetic system in a healthy subject, such as when moving to a standing position. If ACCUVEIN has this capability, it would then represent a simple and rapid diagnostic tool for objectifying a venoconstriction defect in patients with dysautonomia.

Conditions

Interventions

TypeNameDescription
OTHERProgressive standing testProgressive raising test in successive steps in a healthy subject

Timeline

Start date
2025-11-21
Primary completion
2025-12-12
Completion
2025-12-12
First posted
2025-06-19
Last updated
2025-12-24

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT07029191. Inclusion in this directory is not an endorsement.