NCT07029074

Investigation of Inspiratory Muscle Training Applied at Different Intensities on Intercostal Muscle Oxygenation

Investigation of the Acute Effect of Inspiratory Muscle Training Applied at Different Intensities on Intercostal Muscle Oxygenation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (estimated)
• Sponsor: Kirsehir Ahi Evran Universitesi · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

In this study, it was aimed to investigate the acute effect of inspiratory muscle training of different intensities on intercostal muscle oxygenation in healthy individuals.

Detailed description

The functional activity of the respiratory system must be regular and efficient in order to meet the oxygen needs of tissues and organs. The mechanical function of the respiratory system is significantly related to the working capacity of the respiratory muscles. The diaphragm is the primary muscle that provides respiratory functions among the respiratory muscles.The external intercostal muscles help with the inspiration, while the internal intercostal muscles help with the expiration. The basis of inspiratory muscle training is to reduce dyspnea, increase inspiratory muscle function and exercise tolerance. Inspiratory muscle training provides an increase in muscle strength by increasing inspiratory muscle strength, reducing metaboreflex activity and increasing blood flow to the muscles. Training is thought to minimize the effects of activation of inspiratory muscle metaboreflex in both healthy individuals and patients with heart failure. In chronic respiratory patients, forced inspiration effort reduces capillary perfusion of the respiratory muscles, thus increasing the oxygen demand of the muscle. Muscle oxygen saturation shows the oxygen uptake and oxygen consumption of the muscle. It aims to investigate the mechanisms involved in the metaboreflex response to respiratory fatigue in inspiratory muscle training, which severity will acutely reduce it more.

Conditions

• Healthy

Interventions

Type	Name	Description
DEVICE	Sham inspiratory muscle training (MIP 0%)	POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.
DEVICE	MIP 30% inspiratory muscle training	POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.
OTHER	MIP 70% inspiratory muscle training	POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

Timeline

• Start date: 2025-07-23
• Primary completion: 2025-12-23
• Completion: 2026-06-23
• First posted: 2025-06-19
• Last updated: 2025-12-18

Locations

1 site across 1 country: Turkey (Türkiye)