Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07028632

The Safety, Feasibility and Efficacy of NouvNeu001 for Parkinson's Disease

A Phase I/II Study to Assess the Safety, Tolerability and Efficacy of NouvNeu001 Injection for Mid- to Late-stage Parkinson's Disease

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
iRegene Therapeutics Co., Ltd. · Industry
Sex
All
Age
50 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This clinical trial is designed to evaluate the safety, tolerability and preliminary efficacy of a single injection of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in patients with Parkinson's disease.

Detailed description

This is a multi-center, single arm, and open label trial. The NouvNeu001 will be transplanted into bilateral putamen using stereotactic neurosurgery. Subjects will take immunosuppressants to prevent potential immune rejection for 24 to 36 weeks.

Conditions

Interventions

TypeNameDescription
BIOLOGICALHuman Dopaminergic Progenitor CellsSingle injection of Human Dopaminergic Progenitor Cells into the putamen/striatum region of brain.

Timeline

Start date
2025-06-30
Primary completion
2026-12-01
Completion
2030-12-01
First posted
2025-06-19
Last updated
2025-06-29

Locations

1 site across 1 country: China

Regulatory

Source: ClinicalTrials.gov record NCT07028632. Inclusion in this directory is not an endorsement.