NCT07025343

Does Intralipid Infusion Can Reverse the Spinal Anesthesia Effect in Day Case Surgery?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Benha University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the effect of intralipid infusion on reversing the spinal anesthesia effect in day case surgery.

Detailed description

The increasing demand for day-case surgery has led to a growing interest in developing strategies to provide patients with a more convenient, cost-effective, and less invasive alternative to traditional inpatient procedures. Spinal anesthesia, in particular, is a widely used technique in day-case surgery due to its ability to provide excellent analgesia with minimal side effects. Intravenous lipid emulsion therapy is commonly used to treat local anesthetic systemic toxicity (LAST) and has demonstrated some efficacy in treating other drug toxicities, particularly cardiotoxicity from lipophilic drugs.

Conditions

• Intralipid Infusion
• Spinal Anesthesia
• Day Case Surgery

Interventions

Type	Name	Description
OTHER	Lipid emulsion	Patients (\>70kg will receive 100 ml, \<70 will receive 1.5ml/kg) of 20% intravenous lipid emulsion at the end of surgery as a study group.

Timeline

• Start date: 2025-02-01
• Primary completion: 2025-08-31
• Completion: 2025-08-31
• First posted: 2025-06-17
• Last updated: 2025-12-08

Locations

1 site across 1 country: Egypt