NCT07025070

The Link Between Physical Activity and Brain Health in Healthy Adults

The Link Between Strength and Endurance Training and Brain Health in Healthy Adults: A Comparative Study of Former Professional Athletes and Sedentary Individuals

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Technical University of Madrid · Academic / Other
• Sex: All
• Age: 40 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is: Do former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.

Conditions

• Alzheimer Disease
• Inactivity
• Preventive Therapy

Timeline

• Start date: 2024-11-25
• Primary completion: 2026-01-01
• Completion: 2026-09-01
• First posted: 2025-06-17
• Last updated: 2025-06-17

Locations

1 site across 1 country: Spain