NCT07022860

Study on Platelet-Rich Fibrin for Preserving Jawbone After Tooth Extraction Using CBCT Imaging in Adults

Radiographic Assessment of the Effects of Platelet-Rich Fibrin on Socket Preservation: A Case-Control Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Zahedan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if platelet-rich fibrin (PRF), a substance made from a person's own blood, helps preserve the bone in the jaw after tooth extraction in adults. The main questions it aims to answer are: Does PRF help reduce the loss of bone height after tooth removal? Does PRF improve how much of the socket fills with new bone? Researchers will compare extraction sites treated with PRF to untreated sites in the same person to see if PRF helps preserve more bone. Participants will: Have two teeth removed on opposite sides of the mouth Receive PRF in one socket, while the other socket is left to heal naturally Undergo 3D X-ray scans (CBCT) right after extraction and again 3 months later This study will help researchers understand if using PRF alone can improve healing and reduce bone loss after tooth extraction.

Conditions

• Socket Preservation

Interventions

Type	Name	Description
BIOLOGICAL	Platelet-rich fibrin (PRF)	Platelet-rich fibrin (PRF) is an autologous blood-derived material prepared by centrifuging the participant's venous blood without anticoagulants. The PRF clot is then compressed into a membrane and inserted into the extraction socket. It serves as a scaffold rich in platelets and growth factors to support bone regeneration and healing.

Timeline

• Start date: 2024-09-21
• Primary completion: 2025-01-18
• Completion: 2025-01-18
• First posted: 2025-06-15
• Last updated: 2025-06-15

Locations

1 site across 1 country: Iran