NCT07022028

Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 800 (actual)
• Sponsor: Poitiers University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols. To date, no study has compared weaning modalities from mechanical ventilation in patients with these two diseases. Our objective was to assess and compare for ventilator weaning modalities between patients mechanically ventilated for Guillain-Barré syndrome or for myasthenia gravis in a large-scale multicenter study.

Conditions

• Myasthenia Gravis
• Guillain-Barre Syndrome

Timeline

• Start date: 2024-02-27
• Primary completion: 2024-11-06
• Completion: 2024-11-06
• First posted: 2025-06-15
• Last updated: 2025-06-18

Locations

1 site across 1 country: France