Trials / Completed
CompletedNCT07017088
Efficacy of Leuconostoc Mesenteroides
A Randomized Crossover Trial on the Efficacy of Leuconostoc Mesenteroides (VITA-PB2) From Kimchi in Relieving Hangover Symptom
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 28 (actual)
- Sponsor
- Wonju Severance Christian Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
Excessive alcohol intake can cause dehydration, digestive issues, oxidative stress, and hangover symptoms like headache and fatigue. Toxic metabolites like acetaldehyde and ROS contribute to liver damage. Chronic drinking activates harmful pathways like MEOS and increases inflammation. Gut-liver axis disruption also worsens hangovers. Probiotics, such as Leuconostoc mesenteroides, may help restore gut health and reduce toxicity, but more clinical research is needed.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Leuconostoc mesenteroides | Control vs Experiment |
Timeline
- Start date
- 2024-08-13
- Primary completion
- 2024-09-13
- Completion
- 2025-02-28
- First posted
- 2025-06-12
- Last updated
- 2025-06-12
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT07017088. Inclusion in this directory is not an endorsement.