NCT07015710

Gamma Knife Radiosurgery on Tectal Plate Gliomas

Impact of Gamma Knife Radiosurgery on Tectal Plate Gliomas

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 5 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).

Detailed description

Tectal plate gliomas (TPGs) represent a subset of brainstem gliomas that are predominantly slow-growing, low-grade tumors and rarely produce neurological deficits. Viable options include biopsy and monitoring with serial neuroimaging, surgical resection, radiotherapy (either early following surgery or late on evidence of disease progression), chemotherapy, and stereotactic radiosurgery (SRS). SRS using Gamma Knife radiosurgery (GKRS) has been identified in small case series as a safe and promising approach for managing TPGs that necessitate intervention beyond mere observation.

Conditions

• Gamma Knife Radiosurgery
• Tectal Plate Gliomas

Interventions

Type	Name	Description
PROCEDURE	Gamma Knife Radiosurgery	Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Timeline

• Start date: 2021-01-01
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2025-06-11
• Last updated: 2025-06-11

Locations

1 site across 1 country: Egypt