NCT07013435

A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

Thriving Beyond Treatment: A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship.

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 254 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.

Detailed description

The Stress Management and Relaxation Response Resiliency Program for lymphoma survivors (SMART3RP-Lymphoma) was adapted by researchers at the MGH. This group program seeks to buffer stress and promote psychological resiliency and physical well-being through a variety of mind-body approaches, such as imagery, relaxation, and yoga, cognitive behavioral strategies, and positive psychology tools. The main questions it aims to answer are: * Will survivors randomized to SMART3RP-Lymphoma demonstrate greater improvements in quality of life when compared to survivors randomized to a Health Education Program? * Will improvements in resiliency lead to improvements in quality of life? To answer these questions, researchers will compare a resilience intervention tailored to the needs of lymphoma survivors (SMART3RP-Lymphoma) to a Health Education Program to see how they affect quality of life of lymphoma survivors. Participants will: * Fill out 4 surveys across 12 months * Participate in 8 weekly, virtual group sessions * Submit hair cortisol samples

Conditions

• Lymphoma

Interventions

Type	Name	Description
OTHER	Health Education Program	8 weekly sessions that include education on the co-occurrence of mental and physical problems, goal setting for health behavior change, and self-monitoring. Each session includes basic didactic information, interactive application of the information, and open discussion of didactic material.
OTHER	SMART3RP-Lymphoma	The SMART3RP-lymphoma is a group program that, through a variety of mind-body approaches, such as imagery, relaxation, and yoga, seeks to buffer stress and promote psychological resiliency and physical well-being.

Timeline

• Start date: 2026-05-01
• Primary completion: 2029-01-01
• Completion: 2030-01-01
• First posted: 2025-06-10
• Last updated: 2026-03-30

Locations

1 site across 1 country: United States