Trials / Recruiting
RecruitingNCT07013344
Association of Plasma N-terminal Pro-Brain Natriuretic Peptide Levels With the Burden of Coronary Artery Disease
Association of Plasma N-terminal Pro-Brain Natriuretic Peptide Levels With the Burden of Coronary Artery Disease: Insights From a Real-World Cohort
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 800 (estimated)
- Sponsor
- IRCCS Ospedale San Raffaele · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study aim to investigate the association between plasma NT-proBNP levels and the presence, extent and severity of stenosis in patients with suspected coronary artery disease.
Detailed description
The investigators prospectively measured plasma NT-proBNP levels in consecutive patients referred to the center for elective diagnostic coronary angiography due to symptoms or signs of coronary artery disease over a two- year period. Patients with conditions known to elevate NT-proBNP levels, including heart failure, severe valvular disease, atrial fibrillation, severe chronic kidney disease (eGFR \< 30 mL/min), prior coronary artery bypass grafting, or age over 80 years, were excluded.
Conditions
- Chronic Coronary Syndrome
- Chronic Coronary Total Occlusion
- Coronary Arterial Disease (CAD)
- Stable Chronic Angina
- NT-pro-BNP
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | BNP | Measurement of plasma NT-proBNP level. |
Timeline
- Start date
- 2021-09-01
- Primary completion
- 2025-06-29
- Completion
- 2025-07-31
- First posted
- 2025-06-10
- Last updated
- 2025-06-10
Locations
2 sites across 1 country: Italy
Source: ClinicalTrials.gov record NCT07013344. Inclusion in this directory is not an endorsement.