NCT07012252

Optical Coherence Tomography of the Irido-Corneal Angle Before and After Goniotomy and Trabeculotomy in Primary Congenital Glaucoma

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 1 Week – 72 Weeks
• Healthy volunteers: Not accepted

Summary

The research aimed to improve surgical techniques and long-term outcomes by utilizing this advanced imaging technology to illuminate the structural abnormalities of the anterior segment in eyes with primary congenital glaucoma.

Detailed description

Primary congenital glaucoma (PCG) is a rare disease, but it is responsible for 2.5%-15% of all documented cases of pediatric blindness. The main target of the treatment of pediatric glaucoma is to control the IOP surgically. However, medical treatment could be instituted as a temporary and/or adjunctive option to maximize Intraocular pressure (IOP) control. Initial goniotomy or trabeculotomy have been detected to have high success rates. Trabeculotomy has a comparable long-term success rate in most patients of PCG. The success rate of trabeculotomy is lower in advanced or late-presenting patients.

Conditions

• Optical Coherence Tomography
• Anterior Chamber Angle
• Goniotomy
• Trabeculotomy
• Primary Congenital Glaucoma

Interventions

Type	Name	Description
PROCEDURE	Optical coherence tomography	Infants underwent optical coherence tomography.

Timeline

• Start date: 2018-10-01
• Primary completion: 2020-11-01
• Completion: 2020-11-01
• First posted: 2025-06-10
• Last updated: 2025-06-10

Locations

1 site across 1 country: Egypt