NCT07005115

Serum Lipid Profile and Lip Squamous Cell Carcinoma

Analysis of Serum Lipid Profile in Patients With Lip Squamous Cell Carcinoma

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 56 (actual)
• Sponsor: Akdeniz University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational retrospective study is to assess whether serum lipid levels differ between patients diagnosed with lip squamous cell carcinoma (SCC) and healthy individuals. The study aims to evaluate if alterations in lipid parameters, especially LDL levels, are associated with the presence of lip SCC and could serve as potential early biomarkers. The main research questions are: Do patients with lip SCC show significantly lower LDL levels compared to healthy controls? Are there significant differences in total cholesterol (TC), triglycerides (TG), HDL, and VLDL between the two groups? A retrospective analysis was conducted using existing medical records of patients with lip SCC and healthy subjects obtained from 2018-2023.

Detailed description

Demographic data and lipid profile information were collected from 56 patients (28 lip SCC and 28 healthy). The lipid parameters included were total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL) and very low-density lipoprotein (VLDL).

Conditions

• Lipid Profile
• Lipids
• SCC - Squamous Cell Carcinoma
• Lip Cancer
• Oral Cancer

Timeline

• Start date: 2018-01-01
• Primary completion: 2021-01-01
• Completion: 2023-01-01
• First posted: 2025-06-05
• Last updated: 2025-06-06

Locations

1 site across 1 country: Turkey (Türkiye)