NCT07004140

Proving Utility of a New Field-cycling MRI Prototype in Acute Stroke Patients

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: University of Aberdeen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can show changes in the brain within the first day of a stroke due to a blocked blood vessel or bleeding in the brain. The main question it aims to answer is: • Can FCI identify brain tissue that might recover within the first few hours after a stroke begins? Participants will undergo a standard MRI scan and an FCI scan, as soon as possible after hospital admission. Participants who have had a blocked blood vessel will also provide a blood sample and will have a follow up visit at 30 days for repeat of both scans and providing another blood sample.

Conditions

• Stroke Acute

Interventions

Type	Name	Description
OTHER	3T MRI research scan	Baseline MRI scan
OTHER	Field-Cycling Imaging research scan	Baseline FCI scan
OTHER	Follow up 3T MRI research scan	Day 30 3T MRI scan
OTHER	Follow up Field-Cycling Imaging research scan	Day 30 FCI scan
OTHER	Blood samples for clotting experiments in vitro	Thrombi from whole blood from ischaemic stroke patients will be formed and examined using bench top nuclear magnetic resonance (NMR) assays. At baseline and 30 days after stroke onset.

Timeline

• Start date: 2025-09-16
• Primary completion: 2026-05-01
• Completion: 2026-05-01
• First posted: 2025-06-04
• Last updated: 2026-01-27

Locations

1 site across 1 country: United Kingdom