Trials / Active Not Recruiting
Active Not RecruitingNCT07003828
Hemodialysis-Induced Renal Perfusion Decline: Unraveling the Pathophysiological Mechanisms Linking Intradialytic Circulatory Stress to Residual Renal Function Loss
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (actual)
- Sponsor
- Yuanjun Yang · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Residual renal function (RRF) plays a critical role in quality of life and survival in hemodialysis (HD) patients but characteristically declines after the initiation of HD. Owing to incomplete understanding of the pathophysiology underlying RRF decline, protective strategies remain limited. The aim of this study was to characterize the changes in renal perfusion in incident HD patients with preserved RRF during dialysis sessions and to provide new strategies for RRF preservation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | CEUS examinations | CEUS examinations were performed at three predetermined time points during each HD session: immediately before, 3 hours after HD initiation, and 15 minutes post-dialysis. |
Timeline
- Start date
- 2024-05-01
- Primary completion
- 2026-04-30
- Completion
- 2026-04-30
- First posted
- 2025-06-04
- Last updated
- 2025-06-04
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT07003828. Inclusion in this directory is not an endorsement.