NCT07003698

Postoperative Analgesic Efficacy of Recto Intercostal Nerve Block

Postoperative Analgesic Efficacy of Rectointercostal Nerve Block in Patients Undergoing Laparoscopic Cholecystectomy

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Ankara Etlik City Hospital · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Laparoscopic cholecystectomy is a frequently performed surgery and the gold standard for the treatment of symptomatic gallstone disease. Although laparoscopic cholecystectomy is considered minimally invasive, it can cause moderate to severe pain in the postoperative period. Poorly controlled early postoperative pain impairs recovery quality and increases the risk of postoperative pulmonary complications, serving as a risk factor for chronic pain development. Multimodal analgesia, including opioids, is used to manage pain following laparoscopic cholecystectomy. However, opioid treatment may lead to side effects such as postoperative nausea and vomiting (PONV), respiratory depression, and constipation. The primary aim of this study is to evaluate the effect of recto-intercostal nerve block as part of multimodal analgesia on intraoperative opioid consumption and postoperative pain scores in patients undergoing laparoscopic cholecystectomy.

Conditions

• Laparoskopic Cholecystectomy
• Recto Intercostal Nerve Block

Interventions

Type	Name	Description
PROCEDURE	The group without the rectointercostal nerve block	Patients in this group will be administered dexketoprofen 50 mg and tramadol 100 mg intravenously in the intraoperative period. These patients will not receive the rectointercostal nerve block.
PROCEDURE	The rectointercostal plane block	The rectointercostal plane block is performed under ultrasound guidance before the surgical procedure and anesthesia induction, with the patient in the supine position. Additionally, patients in this group will be administered dexketoprofen 50 mg and tramadol 100 mg intravenously in the intraoperative period.

Timeline

• Start date: 2025-06-22
• Primary completion: 2025-12-11
• Completion: 2025-12-21
• First posted: 2025-06-04
• Last updated: 2025-06-04

Locations

1 site across 1 country: Turkey (Türkiye)