NCT07001982

Lumbar Spinal Stenosis and Central Sensitization

The Relationship Central Sensitization, Pain and Depression Patients With Lumbar Spinal Stenosis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 68 (estimated)
• Sponsor: Karabuk University · Academic / Other
• Sex: All
• Age: 45 Years – 80 Years
• Healthy volunteers: —

Summary

Lumbar spinal stenosis (LSS) functionally limits individuals by causing pain in both the waist and the legs during activity and walking. Pain is, therefore, an important problem for patients. Pain lasts for years in LSS and thus becomes chronically persistent. As a result, persistent pain can cause sensitization due to a decrease in the pain threshold. This condition affects patients not only biomedically but also biopsychosocially. For this reason, various sleep disorders and mood disorders can develop in patients. Therefore, this study aimed to examine the relationship between central sensitization and pain, disability, sleep and depression in patients with LSS.

Detailed description

Lumbar spinal stenosis (LSS) functionally limits individuals by causing pain in both the waist and the legs during activity and walking. In particular, the pain in LSS lasts for years and becomes chronic and can cause persistent and disturbing sensitization. This situation may be associated with decreased pain threshold and allodynia. Various studies show that sensitization can affect individuals biomedically and may lead to important health problems. Some of these are sleep and depression problems. Sleep and a healthy mentality are important for continuing daily activities and preserving quality of life. However, when the literature is examined, it is seen that central sensitization and the parameters that may be related to this have not been examined sufficiently. Therefore, the aim of this study is to examine the relationship between central sensitization and pain, disability, sleep and depression in patients with LSS.

Conditions

• Lumbar Spinal Stenosis

Timeline

• Start date: 2025-06-17
• Primary completion: 2025-10-15
• Completion: 2025-12-15
• First posted: 2025-06-03
• Last updated: 2025-06-18

Locations

1 site across 1 country: Turkey (Türkiye)