NCT07001098

Amino Acids for Cardiac Surgery Associated AKI

Amino Acids for the Infant at Risk for Acute Kidney Injury After Cardiac Surgery: A Pilot Study

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 1 Day – 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the feasibility of amino acid infusions in pediatric cardiac surgery patients.

Conditions

• Acute Kidney Injury

Interventions

Type	Name	Description
DRUG	Amino Acids	The participants receive a continuous infusion of a balanced mixture of amino acids (Trophamine) in a dose of 2g/kg/day (max 100g/day) starting at the time of cardiac surgery up to 3 days
DRUG	Placebo	The participants receive a continuous infusion of a lactated ringers (placebo), equivalent volume to amino acids, starting at the time of cardiac surgery up to 3 days

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-11-01
• Completion: 2026-11-01
• First posted: 2025-06-03
• Last updated: 2025-06-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study