NCT07000994

Dobutamine During Major Abdominal Surgery

Dobutamine During Major Abdominal Surgery: A Randomized Pilot Trial (PUSH-1)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.

Conditions

• Intraoperative Myocardial Depression

Interventions

Type	Name	Description
DRUG	Dobutamine	In patient assigned to dobutamine administration, dobutamine (concentration: 5 mg mL-1) will be administered with an infusion rate of 3 µg kg-1 min-1 (ideal body weight).
OTHER	Routine care	In patients assigned to routine care, intraoperative hemodynamic management will be in accordance with routine care.

Timeline

• Start date: 2025-06-16
• Primary completion: 2026-03-01
• Completion: 2026-04-01
• First posted: 2025-06-03
• Last updated: 2025-06-17

Locations

1 site across 1 country: Germany