NCT07000071

Non-invasive Secondary Respiratory Support in Late Preterm and Term Infants

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Alexandria University · Academic / Other
• Sex: All
• Age: 1 Day – 14 Days
• Healthy volunteers: Accepted

Summary

The aim of the present work is to compare between various modes of non-invasive respiratory support (including NCPAP, NIPPV, and NHFOV) as secondary respiratory support modes in late preterm and term neonates as regards the need for reintubation. Additionally, the study aims at comparing between the three modes concerning the associated morbidity and mortality.

Conditions

• Neonates
• Respiratory Distress
• Non- Invasive Ventilation

Interventions

Type	Name	Description
DEVICE	NCPAP	Apply nasal continuous positive airway pressure in intubated patients with respiratory distress at time of weaning
DEVICE	NIPPV	Apply nasal intermittent positive pressure ventilation in intubated patients with respiratory distress at time of weaning
DEVICE	NHFOV	Apply nasal high frequency ventilation in intubated patients with respiratory distress at time of weaning

Timeline

• Start date: 2021-07-01
• Primary completion: 2021-12-30
• Completion: 2022-01-30
• First posted: 2025-05-31
• Last updated: 2025-05-31

Locations

1 site across 1 country: Egypt