NCT06999213

Lower Limb ExoNET: Development and Evaluation for Gait Assistance With Stroke Survivors

• Status: Not Yet Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Shirley Ryan AbilityLab · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Stroke-related gait impairments, such as poor limb coordination, imbalance, and reduced push-off strength, are often addressed using robotic systems or electrical stimulation, which can be costly, invasive, or insufficient for long-term recovery. Current devices often assist movement but fail to promote functional motor learning. Research supports rehabilitation strategies that amplify gait errors to drive neuroplasticity and adaptation. The LegExoNET (Exoskeletal Network for Elastic Torque) is a novel, passive wearable exoskeleton designed to address this need by enabling both assistive and therapeutic gait training. It stores and releases elastic energy to aid movement while allowing natural joint motion. The system aims to support individuals post-stroke transitioning to independent rehabilitation by offering a lightweight, affordable, and adaptive solution. Initial testing will focus on healthy individuals to assess safety and feasibility before expanding to stroke populations. The LegExoNET has the potential to enhance gait recovery and reduce therapist burden through error augmentation and personalized support, both in clinical and at-home settings.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Assist	The device will provide assistive torques to support either ankle, knee, and/or hip movements.
OTHER	Resist	The device will apply resistive torques to exaggerate gait asymmetries, facilitating error augmentation.
OTHER	Slack	The device will be worn but will not generate any torque.

Timeline

• Start date: 2026-01-31
• Primary completion: 2029-12-31
• Completion: 2029-12-31
• First posted: 2025-05-31
• Last updated: 2025-07-30