NCT06996522

UEMR Versus HSP in the Treatment of Pedunculated Colorectal Polyps Less Than 10mm in Size

Underwater Endoscopic Mucosal Resection Versus Hot Snare Polypectomy in the Treatment of Pedunculated Colorectal Polyps Less Than 10mm in Size: A Single-center, Open-label, Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 338 (estimated)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 35 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A prospective, single-center, open-label, randomized controlled study to compare the effectiveness and safety of underwater endoscopic mucosal resection (UEMR) and hot snare polypectomy (HSP) in treating Pedunculated colorectal polyps less than 10mm in size.

Detailed description

1. Patients are undergone screening, surveillance, or therapeutic colonoscopy at the Endoscopy department of Gastrointestinal endoscopy center of Huadong hospital affiliated to Fudan University. 2. Randomize patients with pedunculated colorectal polyps less than 10mm in size into 2 interventional groups based on Random function of Statistical Package for the Social Sciences (SPSS) 20.0, including (1) Group 1: Underwater endoscopic mucosal resection (UEMR) and (2) Group 2: Hot snare polypectomy (HSP). 3. Collecting variables which consist of primary and secodary outcomes.

Conditions

• Pedunculated Colorectal Polyp

Interventions

Type	Name	Description
PROCEDURE	underwater endoscopic mucosal resection	The Pedunculated colorectal polyps less than 10mm in size in this group will be treated by UEMR
PROCEDURE	Hot snare polypectomy	The Pedunculated colorectal polyps less than 10mm in size in this group will be treated by HSP

Timeline

• Start date: 2025-06-01
• Primary completion: 2027-07-31
• Completion: 2027-07-31
• First posted: 2025-05-30
• Last updated: 2025-05-30

Locations

1 site across 1 country: China