NCT06994520

Efficacy of Topical Cannabidiol for Eczema

Efficacy of Topical Cannabidiol in Patients With Eczema

• Status: Active Not Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Khon Kaen University · Academic / Other
• Sex: All
• Age: 25 Years
• Healthy volunteers: Not accepted

Summary

Itching is a common symptom encountered in general medical practice. It can cause significant discomfort, disrupt sleep, and impair patients' quality of life. Chronic pruritic skin conditions such as atopic dermatitis, nummular eczema, lichen simplex chronicus, and prurigo nodularis are frequently observed. The pathogenesis of these conditions remains incompletely understood, and effective long-term treatment options are limited. Current therapies include topical corticosteroids, topical calcineurin inhibitors, oral corticosteroids, and systemic immunosuppressants. However, these treatments are often associated with adverse effects, and the diseases tend to follow a chronic, relapsing course. Therefore, the investigators aim to investigate the efficacy and safety of topical cannabis extract in patients with chronic pruritic skin conditions.

Conditions

• Chronic Pruritus
• Eczema
• Nummular Eczema
• Atopic Dermatitis
• Prurigo Nodularis

Interventions

Type	Name	Description
OTHER	Cannabidiol (CBD)	5%CBD cream
DRUG	Triamcinolone (TAC) 0.1% cream	comparator

Timeline

• Start date: 2025-05-01
• Primary completion: 2026-05-01
• Completion: 2026-12-31
• First posted: 2025-05-29
• Last updated: 2025-05-29

Locations

1 site across 1 country: Thailand