NCT06992856

The Effect of Cap-assisted Water Exchange Colonoscopy on Straight Passage of the Colonoscope Through the Sigmoid Colon, Without Loop Formation

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 531 (estimated)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A prospective, single-center, single-blind, randomized controlled study to compare the proportion of straight passage through the sigmoid colon without loop formation between conventional colonoscope passage, left colon water exchange colonoscope passage, and cap-assisted left colon water exchange colonoscope passage through the sigmoid colon

Detailed description

1. Patients are undergone screening, surveillance, or therapeutic colonoscopy at the Endoscopy department of Gastrointestinal endoscopy center of Huadong hospital affiliated to Fudan University. 2. Randomize patients into 3 interventional groups based on R script (version 4.4.1), including (1) Group 1: Conventional colonoscope passage, (2) Group 2: left colon water exchange colonoscope passage, (3) Group 3: cap-assisted left colon water exchange colonoscope passage. 3. Collecting variables which consist of primary and secodary outcomes.

Conditions

• Colonoscope Passage

Interventions

Type	Name	Description
PROCEDURE	Conventional colonoscope passage	Use conventional colonoscope passage through the sigmoid colon
PROCEDURE	left colon water exchange colonoscope passage	Use left colon water exchange colonoscope passage through the sigmoid colon
PROCEDURE	cap-assisted left colon water exchange colonoscope passage	Use cap-assisted left colon water exchange colonoscope passage through sigmoid colon

Timeline

• Start date: 2025-06-01
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2025-05-28
• Last updated: 2025-05-28

Locations

1 site across 1 country: China