Trials / Not Yet Recruiting
Not Yet RecruitingNCT06989333
Local Spraying of GM-CSF Via Bronchoscopy in the Treatment of Autoimmune Pulmonary Alveolar Proteinosis
A Single-arm Clinical Study of Local Spraying of GM-CSF Via Bronchoscopy in the Treatment of Autoimmune Pulmonary Alveolar Proteinosis
- Status
- Not Yet Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- Sponsor
- Jiuwu Bai · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to explore a new therapeutic approach: the feasibility, safety and preliminary efficacy of directly spraying GM-CSF into the airway through bronchoscopy for the treatment of aPAP.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GM-CSF (granulocyte-macrophage colony-stimulating factor) | Bronchoscopy under general anesthesia or sedation; The predetermined dose of recombinant GM-CSF was dissolved in normal saline. The diseased lung segments were located through bronchoscopy and the liquid medicine was sprayed. |
Timeline
- Start date
- 2025-07-01
- Primary completion
- 2027-06-30
- Completion
- 2027-06-30
- First posted
- 2025-05-25
- Last updated
- 2025-05-25
Source: ClinicalTrials.gov record NCT06989333. Inclusion in this directory is not an endorsement.