NCT06987838

Effect of Virtual Reality on Prostaglandin Levels in Adolescent Females With Primary Dysmenorrhea

Effect of Virtual Reality on Prostaglandin Levels in Adolescent Females With Primary Dysmenorrhea: A Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Benha National University · Academic / Other
• Sex: Female
• Age: 17 Years – 21 Years
• Healthy volunteers: Not accepted

Summary

This study will be conducted to study the effect of virtual reality therapy on prostaglandin levels in adolescent females with primary dysmenorrhea.

Detailed description

Primary dysmenorrhea is thought to be caused by excessive levels of prostaglandins, which are hormones that stimulate the uterus to contract during menstruation and childbirth, Treatment must be tailored to individual patient symptoms. Pharmacologic management with non-steroidal anti-inflammatory medications and/or combined hormonal contraceptives is most common. Heat therapy, exercise, vitamins and dietary supplements have limited evidence and can be offered for patients seeking non-pharmacologic adjunctive or alternative options. Greater awareness for both health-care providers and patients allow for early intervention to reduce impact on quality of life and life course potential. The significance of this study to assess the effect of virtual reality therapy on primary dysmenorrhea.

Conditions

• Primary Dysmenorrhea

Interventions

Type	Name	Description
DRUG	Pharmacological treatment	All participants in the two groups will receive pharmacological treatment in the form of ibuprofen 400 mg, three times per day, during the first 2 days of menstruation, for 3 menstrual cycles.
OTHER	Virtual reality	The experimental group will receive virtual reality during the first 2 days of menstruation, for 3 menstrual cycles.

Timeline

• Start date: 2025-05-25
• Primary completion: 2025-08-25
• Completion: 2025-09-01
• First posted: 2025-05-23
• Last updated: 2025-05-23

Locations

1 site across 1 country: Egypt