NCT06986577

Effect of Mechanical Ventilation on Cardiac RF Ablation

Evaluation of Mechanical Ventilation Methods Applied During the Procedure in Pediatric Cardiac Radiofrequency Ablation Interventions: Prospective Observational Study

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Izmir City Hospital · Other Government
• Sex: All
• Age: 0 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to describe the results of cardiac radiofrequency ablation under general anesthesia. to evaluate mechanical ventilation methods in pediatric patients. The main questions it aims to answer are 1. Whether lower tidal volume high frequency mechanical ventilation effects the success of radiofrequency ablation in pediatric cardiac arryhtmia patient? 2. The effect of mechanical ventilation strategies on the number of effective lesions, radiofrequency ablation time and arrhythmia recurrence in the first month

Detailed description

Radiofrequency ablation (RF) is an effective method for the threatment of cardiac arrhythmias in pediatric patients. General anaesthesia and mechanical ventilation is the most common anesthesia management for pediatric arrhythmia patients. During the prosedure, thoracic excursion results in displacement of the catheter and disrupts the catheter stability which is crucial for quality of contact force (CF), sufficient ablation and safety. To minimize the thoracic excursion, high frequency low tidal volume ventilation and apnea ventilation may be needed during radiofrequency ablation. According to investigators knowledge there are studies about ventilatory strategies in adult patients who underwent cardiac radiofrequency ablation. However, there are no studies corcerning pediatric patients. In this study investigators aimed to investigate best ventilatory strategy for minimize thoracic excursion in pediatric patients with general anaesthesia. In this study investigators are going to observe 3 different ventilation strategies on radiofrequency ablation. 1. Lung protective mechanical ventilation with 7-9 ml/kg tidal volume, 2. Low tidal volume (4 ml/kg) high frequency mechanical ventilation 3. Apnea ventilation during radiofrequency ablation

Conditions

• Radiofrequency Catheter Ablation

Timeline

• Start date: 2025-01-30
• Primary completion: 2026-02-10
• Completion: 2026-02-27
• First posted: 2025-05-23
• Last updated: 2026-01-29

Locations

1 site across 1 country: Turkey (Türkiye)