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Trials / Completed

CompletedNCT06983704

Assessing Combined Bevacizumab-Mitomycin C Use During Ahmed Valve Revision in Recurrent Pediatric Glaucoma

Evaluation of Combined Bevacizumab-Mitomycin C Use During Ahmed Valve Revision in Recurrent Pediatric Glaucoma

Status
Completed
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
50 (actual)
Sponsor
Benha University · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

To asess the efficacy and safety of combining subconjunctival bevacizumab with mitomycin C (MMC) during AGV revision surgery in pediatric patients with recurrent glaucoma.

Detailed description

Recurrent pediatric glaucoma following Ahmed Glaucoma Valve (AGV) implantation presents a therapeutic challenge. This study evaluates the efficacy and safety of combining subconjunctival bevacizumab with mitomycin C (MMC) during AGV revision surgery in pediatric patients with recurrent glaucoma.

Conditions

Interventions

TypeNameDescription
PROCEDUREAGV plateAGV plate using a 27-gauge needle
PROCEDUREbevacizumab injectionsubconjunctival injection of bevacizumab

Timeline

Start date
2024-02-09
Primary completion
2025-02-08
Completion
2025-02-15
First posted
2025-05-21
Last updated
2025-05-21

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT06983704. Inclusion in this directory is not an endorsement.

Assessing Combined Bevacizumab-Mitomycin C Use During Ahmed Valve Revision in Recurrent Pediatric Glaucoma (NCT06983704) · Clinical Trials Directory