NCT06978348

Research on Early Prediction Model of Ischemic Cerebrovascular Disease Based on Artificial Intelligence Technology.

Establish an Artificial Intelligence Clinical Decision Support System for Patients With Carotid/Vertebral Artery Stenosis.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 244,296 (estimated)
• Sponsor: Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Establish an artificial intelligence clinical decision support system for patients with carotid/vertebral artery cerebrovascular stenosis, early identification of patients who may have cerebral infarction. With the support of this project, it is expected that a secondary prevention clinical decision support system for chronic stroke will be established, which is likely to become an important auxiliary tool for the management of cerebrovascular diseases in the future.

Detailed description

Stroke is a disease with a high mortality rate and incidence rate, and it is one of the main reasons for high medical expenses. Ischemic stroke accounts for approximately 85% of all subtypes of stroke. Carotid artery and vertebral artery stenosis are definite and intervenable risk factors for ischemic stroke. However, the selection of clinical intervention timing and methods for patients with cerebrovascular stenosis is limited to the rate of carotid/vertebral artery stenosis and the symptoms of the patients. Cerebral infarction caused by carotid/vertebral artery stenosis often leads to irreparable neurological deficits. Currently, there is a lack of comprehensive evaluation methods for the severity of ischemic cerebrovascular diseases such as carotid/vertebral artery stenosis, and even less a clinical decision-making system that can predict the progression of the disease. This project intends to take the demographic data and clinical information of patients with cerebrovascular stenosis from multiple centers and ethnic groups as the entry point, combine the multidisciplinary advantages of imaging, ultrasound, clinical medicine and computer science, and use artificial intelligence technology to construct a model for predicting the disease progression and the probability of adverse cardiovascular events such as stroke in patients with cerebrovascular stenosis. Based on this, the investigators' hospital intends to develop a set of secondary prevention management tools and clinical decision support systems for ischemic cerebrovascular diseases.

Conditions

• Ischemic Cerebrovascular Disease
• Artificial Intelligence
• Prediction Model

Timeline

• Start date: 2025-05-10
• Primary completion: 2025-06-10
• Completion: 2025-06-10
• First posted: 2025-05-18
• Last updated: 2025-05-18

Locations

1 site across 1 country: China