NCT06975358

Accelerated Orthodontics With Alveolar Decortication Plus CGF Injection

Impact of Alveolar Decortication Combined With CGF Injection on Acceleration of Maxillary Canine Retraction-A Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Safa Basiouny Alawy · Academic / Other
• Sex: All
• Age: 16 Years – 22 Years
• Healthy volunteers: Not accepted

Summary

The aim of the present study is to evaluate alveolar bone decortication combined with CGF Injection on tooth movement acceleration

Conditions

• Accelerate Tooth Movement

Interventions

Type	Name	Description
PROCEDURE	Alveolar decortication plus CGF injection	Experimental sides will receive CGF injection (70 units) disto-buccal and disto-palatal to the maxillary canine after performing decortication. After administration of local anesthesia, two-line flap will be performed from the mesial surface of the maxillary second premolar to the distal surface of the maxillary canine Mucoperiosteal flap will be reflected in the buccal side. Two millimeters of marginal crestal bone will be held intact and using a high-speed drill and a round carbide bur (1mm diameter) under copious saline irrigation, the cortical wall will be penetrated to reach marrow spaces. Multiple perforations (10 holes for standardization) in the cortical bone will be created. The surgical site will then rinsed, and the flap will be repositioned and sutured.
PROCEDURE	canine retraction without acceleration	in the control side, the maxillary canine will be retracted without any acceleration procedure

Timeline

• Start date: 2025-05-20
• Primary completion: 2025-10-01
• Completion: 2025-11-01
• First posted: 2025-05-16
• Last updated: 2025-06-27

Locations

1 site across 1 country: Egypt