NCT06974643

Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy

Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy: A Randomized Non-inferiority Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare paravertebral block and thoracic epidural in awake thoracotomy.

Detailed description

Pain can often persist after thoracotomy, and the incidence of chronic pain is high, with studies revealing that 30% to 50% of patients still experience pain up to five years after surgery. Thoracic epidural blockade (TEB) blocks nerves that supply the chest with local anesthetic bilaterally, at the spinal cord level. It acts by reducing the onward transmission of painful nerve signals, but may not abolish them altogether. Paravertebral blockade (PVB) involves injecting local anesthetic into the paravertebral space, which contains spinal nerves (and sometimes even extension of the dura), white and grey rami communicantes, the sympathetic chain, and intercostal vessels, on the side of surgery.

Conditions

• Thoracic Epidural Anesthesia
• Paravertebral Block
• Awake Thoracotomy

Interventions

Type	Name	Description
OTHER	Thoracic epidural block	Patients will preoperatively receive an awake thoracic epidural block.
OTHER	Paravertebral block	Patients will preoperatively receive a paravertebral block.

Timeline

• Start date: 2025-05-15
• Primary completion: 2025-10-01
• Completion: 2025-10-01
• First posted: 2025-05-16
• Last updated: 2025-05-16

Locations

1 site across 1 country: Egypt