NCT06973889

Evaluation of IgY Antibody Efficacy in Egg Yolk Against Helicobacter Pylori in Bacterial Elimination and Clinical Symptoms Improvement of Gastrointestinal Patients

Evaluation of IgY Antibodies Effectiveness in Egg Yolk Against Helicobacter Pylori in Removing Bacteria and Improving Clinical Symptoms in the Patients

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Mashhad University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 78 Years
• Healthy volunteers: Not accepted

Summary

1. Investigating its effectiveness in removing bacteria in invivo conditions 2. Investigating the effectiveness in improving the clinical symptoms of patients

Conditions

• HELICOBACTER PYLORI INFECTIONS
• Gastrointestinal Disease

Interventions

Type	Name	Description
BIOLOGICAL	Helicobacter pylori eradication therapy	12 grams of egg yolk powder containing about 2 grams of antibody twice a day for 2 weeks along with usual antibiotic treatment including OAC or omeprazole (40 mg/day), clarithromycin (1000 mg/day) and amoxicillin (2000 mg/day).

Timeline

• Start date: 2023-12-04
• Primary completion: 2024-12-30
• Completion: 2025-01-21
• First posted: 2025-05-15
• Last updated: 2025-05-15

Locations

2 sites across 1 country: Iran