NCT06969144

Subtotal Cholecystectomy for Difficult Gall Bladder Due to Chronic Cholecystitis

Subtotal Cholecystectomy for Difficult Gall Bladder Due to Chronic Cholecystitis: A Cross-sectional Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,149 (actual)
• Sponsor: Tribhuvan University Teaching Hospital, Institute Of Medicine. · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Subtotal cholecystectomy (STC) is a valuable technique when severe inflammation, fibrosis, or anatomical variations obscure the critical view of safety essential for identifying the cystic duct and artery. It helps reduce the risk of bile duct injuries and other complications that arise during a total cholecystectomy (TC) when these structures are not visible. This study evaluates the safety and outcomes of subtotal cholecystectomy in chronic cholecystitis.

Detailed description

A retrospective analysis was conducted in all patients who underwent a cholecystectomy between May 2021 and November 2024. Indications, complications, and perioperative outcomes of STC were compared with those of standard TC. The investigators concluded STC is an important bailout procedure in a difficult laparoscopic cholecystectomy associated with higher early postoperative complications but lower bile duct injury.

Conditions

• Gallstone

Interventions

Type	Name	Description
PROCEDURE	cholecystectomy	The indications for elective cholecystectomy were symptomatic cholelithiasis, a GB polyp more than ten millimeters, a history of cholecystitis, biliary pancreatitis, or choledocholithiasis. Patients with cholecystitis and severe or moderately severe pancreatitis were operated on after six weeks of the event. Other patients received surgery at the earliest available date. All patients with choledocholithiasis underwent endoscopic retrograde cholangiopancreatography (ERCP) and stone clearance before cholecystectomy. Patients who underwent laparoscopic cholecystectomy were evaluated by surgical and anesthesia teams in outpatient clinics and co-morbid conditions were optimized. Preoperative antibiotic prophylaxis was given to all the patients before induction of anesthesia.

Timeline

• Start date: 2024-12-23
• Primary completion: 2025-01-12
• Completion: 2025-01-13
• First posted: 2025-05-13
• Last updated: 2025-05-13

Locations

1 site across 1 country: Nepal