NCT06968091

Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients: A Randomized Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 168 (actual)
• Sponsor: Zhejiang Cancer Hospital · Academic / Other
• Sex: All
• Age: 65 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study investigated the effect of Trendelenburg position on preventing post-induction hypotension in elderly patients undergoing abdominal surgery with general anesthesia. The patients will receive the 10° Trendelenburg position or supine position during anesthesia induction. The primary outcome is the area under a mean arterial pressure (MAP) below 65 mm Hg within the first 15 minutes during anesthesia induction.

Conditions

• Hypotension on Induction
• Old Age

Interventions

Type	Name	Description
OTHER	Trendelenburg position	After the loss of consciousness during general anesthesia, the 10° Trendelenburg position is adopted.
OTHER	Supine Horizontal Position	After the loss of consciousness during general anesthesia, the Supine Horizontal Position is adopted.

Timeline

• Start date: 2025-05-16
• Primary completion: 2026-04-01
• Completion: 2026-04-03
• First posted: 2025-05-13
• Last updated: 2026-04-09

Locations

1 site across 1 country: China