NCT06966349

Quantifying Ocular Surface Aberrations After Tear Film Interventions

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: University of Waterloo · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Accepted

Summary

The CA-800 Corneal Analyzer (Visia Imaging S.R.L., Italy) is a device that can measure small imperfections in the tear film when the eyes are open. The goal of this study is to see if the device can detect changes in the tear film after instillation of an eye drop or when contact lenses are worn.

Conditions

• Tear Film Characteristics

Interventions

Type	Name	Description
DRUG	Systane Complete Preservative-Free	One drop of Systane Complete Preservative Free will be instilled in each eye. Higher order aberrations assessed before and after instillation.
DEVICE	Senofilcon A	Daily disposable silicone hydrogel contact lenses indicated for myopia or hyperopia. Higher order aberrations assessed before and after instillation.
DEVICE	Somofilcon A	Daily disposable silicone hydrogel contact lenses indicated for myopia or hyperopia. Higher order aberrations assessed before and after instillation.

Timeline

• Start date: 2025-06-10
• Primary completion: 2025-12-15
• Completion: 2025-12-15
• First posted: 2025-05-11
• Last updated: 2025-10-21

Locations

1 site across 1 country: Canada

Regulatory

• FDA-regulated drug study
• FDA-regulated device study