NCT06964555

Effect of Intravenous Low-Dose Ketamine Infusion With Intravenous Lignocaine Infusion on Post-Operative Pain in Patients Undergoing Laparoscopic Choleysystectomy Under General Anesthesia

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Fazaia Ruth Pfau Medical College · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Objective: To determine the effect of low-dose ketamine versus lignocaine on post-operative pain in patients undergoing LC under general anesthesia in a tertiary care hospital. Sample Selection: Patients of both the gender of age at least 18 years, planned for elective LC with ASA grade I-II were included. Patients with obesity, history of alcohol consumptions, drug abusers, uncontrolled hypertension and diabetics, with chronic pain, allergic to study drugs, having neurological disorders, unable to understand pain scoring system and converted to open LC were excluded.

Conditions

• Cholelithiases

Interventions

Type	Name	Description
DRUG	Intravenous Ketamine Infusions	Ketamine group received ketamine at 0.2mg/kg bolus intravenously followed by ketamine infusion at rate of 0.2mg/kg/hr throughout the surgery.
DRUG	Intravenous lignocaine	IV Lignocaine was given at the rate of 1 mg/kg/hr.

Timeline

• Start date: 2024-01-01
• Primary completion: 2024-11-30
• Completion: 2024-12-31
• First posted: 2025-05-09
• Last updated: 2025-05-22

Locations

1 site across 1 country: Pakistan