NCT06963723

Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,000 (estimated)
• Sponsor: Alliance Foundation Trials, LLC. · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

The study aims to determine whether monthly remote digital financial hardship screening among adults with advanced/metastatic cancer, undergoing outpatient systemic therapy with non-curative intent, improves patient-centered outcomes, including financial worry, health-related quality of life (HRQoL), symptom burden, patient-reported cancer treatment adherence, and exploratory outcomes of overall survival, patient-reported economic burden, patient-reported support received, patient-reported financial coping strategies, and health insurance literacy.

Detailed description

Financial hardship is a common problem that affects patients treated for advanced cancer and leads to poor outcomes related to financial worry, health related quality of life (HRQoL), symptom burden, treatment adherence, and overall survival. Prior studies have shown that financial navigation may be an effective strategy to attenuate the impact of financial hardship. However, patients and clinicians have identified communication as a key barrier that prevents patients from being connected to sources of financial assistance. To address this critical gap in patient care, and based on strong preliminary data that financial hardship screening may improve patient outcomes, this financial hardship screening intervention will help connect patients to financial navigation resources. It is hypothesized that by connecting patients experiencing financial hardship with financial navigation resources, this intervention will lead to improved patient-centered outcomes.

Conditions

• Advanced Cancer
• Metastatic Cancer

Interventions

Type	Name	Description
OTHER	Financial Hardship Screening	Financial Hardship Screening and Financial Needs Assessment
OTHER	Enhanced Usual Care	Enhanced Usual Care

Timeline

• Start date: 2025-07-01
• Primary completion: 2028-10-01
• Completion: 2029-04-01
• First posted: 2025-05-09
• Last updated: 2026-03-04

Locations

5 sites across 2 countries: United States, Puerto Rico